Jubilant Biosys is hiring for Senior Research Scientist/ Team Lead | Apply Now

Jubilant Biosys is hiring for Senior Research Scientist/ Team Lead (Ph.D in Organic Chemistry)

Jubilant Biosys is hiring for Senior Research Scientist/ Team Lead | Apply Now

Department: DMPK
Position: Team Lead / Senior Research Scientist
Qualification: PhD (Organic Chemistry)
Location: Bangalore
Roles & Responsibilities:

  • Responsible for drug metabolism and pharmacokinetic support for discovery programs.
  • Support preclinical bioanalysis
  • Monitor Pharmacokinetics studies and support bioanalysis
  • Providing pre-clinical ADME lead optimization support to small molecule Drug Discovery
  • programs (Hit Identification to Clinical Candidate Selection) including Inflammation,
  • Neuroscience, Metabolic Disorders and Anti-infective Research.
  • Working as a “DMPK subject matter lead” in multidisciplinary/cross functional teams of drug
  • discovery projects.
  • Understand the Chemical Structure – ADME relationships and design apt strategies towards
  • improving Drug like Properties of the New Chemical Entities.
  • Understand the broader ADME requirements of various projects
  • Conduct PK and PK/PD analysis through early pre-clinical development, and collaborate in
  • PK/PD and efficacy study designs
    Collaborate with safety assessment group (in need basis) on study design
  • Design tailor made ADME protocols for various projects
  • Collate the obtained results and prepare presentations for internal and external meetings
  • Contribute to the design of the critical path for various projects
  • Prediction of human pharmacokinetic properties from in vitro and in vivo data
  • Managing PK and PK/PD analysis through early pre-clinical development, and collaborates in
  • PK/PD and efficacy study design developing robust PK/PD models
  • Prediction of human pharmacokinetic properties from in vitro and in vivo data in preclinical
  • species.
  • Collaborates with safety assessment group on study design.
  • Method validations and analytical trouble shooting; Data generation, compilation, report
  • preparation; Lab note book, record keeping; SOP writing
  • Candidate experience:
  • Ph.D with expertise in Bioanalysis using LC-MS/MS under GLP and non-GLP environment, can lead
  • project as DMPK representative, quantitation of small molecule using LC-MS/MS and can perform
  • metabolite identification work on High resolution mass spectrometry.

For more details visit https://bit.ly/32tTRnm

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